LINK-J & UC San Diego Joint Webinar Series #7 with Osaka University "Mechano-Driven Functionalization of Engineered Tissues" Session 3 Biomaterials/Nanomaterials

Abstract

Dr. Christman's talk
This talk will cover injectable biomaterial based strategies to encourage endogenous tissue healing as well as for drug delivery for several applications in cardiovascular disease and women's health.

Dr. Sakai's talk
Enzymes which function under mild condition for mammalian are attractive tools in tissue engineering. The substrate specificity and mild reaction condition enable us to manufacture and modify the environment around cells without causing adverse effects. My lab’s main works are developments of hydrogels gellable through enzymatic cross-linking and degradable using enzymes, and applications of the hydrogels to tissue engineering. Especially, we focus on the use of horseradish peroxidase for hydrogelation and the use of natural polymers. In addition, we are developing 3D bioprinting techniques suitable for the enzymatic hydrogelation. Apart from these works, we are developing genome-editing technologies using biocompatible polymers. I will introduce these recent works in my presentation.

Biography

Dr. Andrew McCulloch, Distinguished Professor of Bioengineering and Medicine; Director, Institute of Engineering in Medicine, UC San Diego

Dr. Andrew McCulloch is Distinguished Professor of Bioengineering and Medicine at the University of California San Diego and Director of the Institute for Engineering in Medicine. He earned his bachelor (1981) and Ph.D. (1986) degrees in Engineering Science at the University of Auckland and joined the UC San Diego faculty in 1987. He directs the UCSD Interfaces Graduate Training Program and the Interdisciplinary Ph.D. Specialization in Multi-Scale Biology. Dr. McCulloch served as Vice Chair of the Bioengineering Department from 2002 to 2005 and Chair from 2005 to 2008. He is also a member of Qualcomm Institute, the Center for Research on Biological Systems, and a Senior Fellow of the San Diego Supercomputer Center.

Dr. Masahiro Kino-oka, Professor, Department of Biotechnology, Graduate School of Engineering, Osaka University

[Organization]
2000.02.01 - 2003.03.31, Department of Materials Engineering Science, Graduate School of Engineering Science, Associate Professor
2003.04.01 - 2007.03.31, Department of Materials Engineering Science, Graduate School of Engineering Science, Associate Professor
2007.04.01 - 2009.03.31, Department of Materials Engineering Science, Graduate School of Engineering Science, Associate Professor
2009.04.01 - 2020.03.31, Division of Science and Biotechnology, Graduate School of Engineering, Professor
2020.04.01 - , ., Graduate School of Engineering, Professor
[Education]
1989.03　Osaka University Faculty of Engineering Science Graduated
1991.03　Osaka University Graduate School, Division of Engineering Science Completed
1991.05　Osaka University Graduate School, Division of Engineering Science Unfinished
1996.01　Osaka University Graduate School, Division of Engineering Science
[Employment Record]
1991.06 - 2000.01　Osaka Univeristy, Research Associate
2000.02 - 2003.03　Osaka Univeristy, Assistant Professor
2003.04 - 2009.03　Osaka University, Associate Professor
2009.04 -　Professor, Dept. of Biotechnology, Osaka University
[Research topics]
Tissue culture, Bioreactor design, Process design, Image analysis, Regenerative medicine, Drug screening system, Biofunction and bioprocess engineering-related, Biomedical engineering-related

Dr. Karen L. Christman, Professor of Bioengineering & Associate Dean for Faculty, Jacobs School of Engineering, UC San Diego

Christman's research group focuses on developing novel biomaterials for tissue engineering and regenerative medicine applications. The lab has a strong translational focus with the main goal of developing minimally invasive, biomaterials based therapies for myocardial infarction, heart failure, peripheral artery disease and "women's health." Projects are highly interdisciplinary and involve collaborations with basic scientists, engineers and physicians.
She joined the Department of Bioengineering at UC San Diego in 2007 and is a member of the Institute of Engineering in Medicine and the Sanford Consortium for Regenerative Medicine. She is a fellow of the American Heart Association and the American Institute for Medical and Biological Engineering. She is also co-founder of Ventrix, Inc., which is in clinical trials with the cardiac extracellular matrix hydrogel technology developed in her lab at UC San Diego.
She received her B.S. in Biomedical Engineering from Northwestern University in 2000 and her Ph.D. from the University of California San Francisco and Berkeley Joint Bioengineering Graduate Group in 2003, where she examined in situ approaches to myocardial tissue engineering. She was also a NIH postdoctoral fellow at the University of California, Los Angeles in the fields of polymer chemistry and nanotechnology.

Dr. Shinji Sakai, Professor, Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
1998 Chemical Engineering, Faculty of Engineering, Kyushu University Graduated
2000 Kyushu University Graduate School, Division of Engineering Completed
2002 Kyushu University Graduate School, Doctor of Engineering Completed
2002.10 - 2009.12 Research Associate, Assistant Professor, Faculty of Engineering, Kyushu University Graduate School
2010.1 - 2016.3 Associate Professor, Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
2016.4 - Professor, Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University