AMED -Gene & Cell Therapy Symposium－遺伝子・細胞治療シンポジウム－

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医学・医療の進歩に伴い、細胞内の遺伝子、あるいは細胞そのものを使ったアプローチで、がん・難病などを治療することが可能になってきました。しかしながら、比較的新しい治療法である遺伝子治療、細胞治療には、効果の有効性、安全面、製造面でまだ多くの課題があります。
本ワークショップでは米国ペンシルバニア大学より、本分野で数多くの研究開発に携わっておられるJames M. WILSON先生、シンガポールA*STAR分子・細胞生物研究所よりJohn CONNOLLY先生らをお招きし、日本の細胞治療分野の研究者等、専門家を迎え、「遺伝子治療」「細胞治療」をテーマとし、治療方法の確立に向けた医療研究開発の現状と課題について、最新の事例を基に今後の研究開発について討論していただきます。

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0222_GeneCellTherapy_AMED_flyerFix.pdf

日時：2020年2月22日（土）13:00-19:30 （開場 12:30 ）

会場：

日本橋ライフサイエンスビルディング2階201大会議室

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プログラム

Opening Remark
13:00-13:05	Prof Makoto SUEMATSU (President, AMED)
Gene Therapy Session
Session I: Research and Development of Gene Therapy with AVV Chair: Prof Takashi SHIMADA（Nippon Medical School, AMED PO）
13:05-13:35	<Keynote Lecture> Chair: Prof Makoto SUEMATSU Prof James M. WILSON Director, Rose H. Weiss Orphan Disease Center /Perelman School of Medicine, University of Pennsylvania Gene therapy and genome editing for inherited diseases
13:35-13:55	<Keynote Lecture> Ms Monique MOLLOY Executive Director, Research Administration /Perelman School of Medicine, University of Pennsylvania Overview of Gene Therapy Programs and the Orphan Disease Center at UPenn
13:55-14:10	Prof Takanori YAMAGATA Department of Pediatrics, Jichi Medical University Gene therapy improved motor and mental function of patients with AADC deficiency
14:10-14:20	Dr.Yoshie KUROKAWA Department of Pediatrics, Jichi Medical University Gene therapy in a murine model of Niemann-Pick disease type C
14:20-14:35	Prof Hitoshi OSAKA Department of Pediatrics, Jichi Medical University Gene therapy for Glucose Transporter Type-1 (GLUT-1) deficiency
14:35-14:50	A/Prof Yoshihiro ASANO Department of Cardiovascular Medicine, Graduate School of Medicine, Osaka University Development of AAV vectors aiming the gene therapy for cardiomyopathy
14:50-15:05	Prof Shin Kwak Neurologist/Professor Department of Molecular Neuropathogenesis (Endowed Chair, GTRI) Tokyo Medical University Development of gene therapy for amyotrophic lateral sclerosis based on molecular mechanisms
15:05-15:20	Prof Hitoshi OKAZAWA Chair, Neurology, Medical Research Institute/Director, Center for Brain Integration Research, Tokyo Medical and Dental University Development of gene therapies of neurodegenerative diseases targeting new pathological mechanisms
Coffee Break (10min)
Cell Therapy Session
Opening Remark
15:30-15:35	Opening Remark Prof Hiroshi SHIKU Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine
Session II: Cell Therapy - a focus on quality, efficacy and safety Chair: Prof Hiroshi SHIKU (Japan)
15:35-16:05	<Keynote Lecture> A/Prof John CONNOLLY Director for Translational Immunology, Institute of Molecular and Cell Biology (IMCB), ASTAR Systems based approach to monitoring cells therapy clinical trials*
16:05-16:35	<Keynote Lecture> Prof Toshio SUDA Senior Principal Investigator, Cancer Science Institute of Singapore/ Professor, Department of Medicine, Yong Loo Lin School of Medicine, NUS Hematopoietic stem cells and their niche
Session III: Cell Therapy - Kick-off Presentations of SICORP Singapore Chair: A/Prof John CONNOLLY (Singapore), Prof Hiroshi SHIKU (Japan)
16:35-16:55	Dr Shoji SAITO (Japan) Assistant Professor, Shinshu University, Department of Paediatric, School of Medicine Dr Timothy Wai Ho Shuen (Singapore) Research Fellow, National Cancer Center Singapore Developing a safe and potentially efficacious piggyBac-based CAR-T cell strategy for virus-related cancers
16:55-17:15	Dr Tatsuto KAGEYAMA (Japan) Researcher, Kanagawa Institute of Industrial Science and Technology (KISTEC) Dr Michinao HASHIMOTO (Singapore) Assistant Professor, Singapore University of Technology and Design Large-scale Preparation of Hair Follicle Germs using Hydrogel Bioprinting
17:15-17:35	Dr Jun SHIRAKAWA (Japan) Assistant Professor, Yokohama City University, Graduate School of Medicine Dr Adrian Kee Keong TEO (Singapore) Principal Investigator, Institute of Molecular and Cell Biology, ASTAR Human stem cell-derived pancreatic beta cells for the treatment of diabetes*
Panel Discussion
17:35-18:05	Panellists: Dr Shoji SAITO (Japan) Dr Timothy Wai Ho Shuen (Singapore) Dr Tatsuto KAGEYAMA (Japan) Dr Michinao HASHIMOTO (Singapore) Dr Jun SHIRAKAWA (Japan) Dr Adrian Kee Keong TEO (Singapore)
Closing Remark
18:05-18:10	A/Prof John CONNOLLY (Director for Translational Immunology, IMCB, A*STAR)
Reception
18:30-19:30	Foyer at 10th floor of Nihonbashi Life Science Building (Supported by LINK-J)