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医学・医療の進歩に伴い、細胞内の遺伝子、あるいは細胞そのものを使ったアプローチで、がん・難病などを治療することが可能になってきました。 しかしながら、比較的新しい治療法である遺伝子治療、細胞治療には、効果の有効性、安全面、製造面でまだ多くの課題があります。
本ワークショップでは米国ペンシルバニア大学より、本分野で数多くの研究開発に携わっておられるJames M. WILSON先生、シンガポールA*STAR分子・細胞生物研究所よりJohn CONNOLLY先生らをお招きし、日本の細胞治療分野の研究者等、専門家を迎え、「遺伝子治療」「細胞治療」をテーマとし、治療方法の確立に向けた医療研究開発の現状と課題について、最新の事例を基に今後の研究開発について討論していただきます。
※同時通訳あり（同時通訳のレシーバーの台数には限りがございますので、必要な方のみへのご提供となりますこと、ご容赦ください。）
※ご好評につき満席となりました。キャンセル待ちをご希望の方は問合せ先までご連絡くださいませ。
プログラム
| Opening Remark | |
| 13:00-13:05 | Prof Makoto SUEMATSU (President, AMED) |
| Gene Therapy Session | |
| Session I: Research and Development of Gene Therapy with AVV Chair: Prof Takashi SHIMADA（Nippon Medical School, AMED PO） |
|
| 13:05-13:35 | <Keynote Lecture> Chair: Prof Makoto SUEMATSU Prof James M. WILSON Director, Rose H. Weiss Orphan Disease Center /Perelman School of Medicine, University of Pennsylvania Gene therapy and genome editing for inherited diseases |
| 13:35-13:55 | <Keynote Lecture> Ms Monique MOLLOY Executive Director, Research Administration /Perelman School of Medicine, University of Pennsylvania Overview of Gene Therapy Programs and the Orphan Disease Center at UPenn |
| 13:55-14:10 | Prof Takanori YAMAGATA Department of Pediatrics, Jichi Medical University Gene therapy improved motor and mental function of patients with AADC deficiency |
| 14:10-14:20 | Dr.Yoshie KUROKAWA Department of Pediatrics, Jichi Medical University Gene therapy in a murine model of Niemann-Pick disease type C |
| 14:20-14:35 | Prof Hitoshi OSAKA Department of Pediatrics, Jichi Medical University Gene therapy for Glucose Transporter Type-1 (GLUT-1) deficiency |
| 14:35-14:50 | A/Prof Yoshihiro ASANO Department of Cardiovascular Medicine, Graduate School of Medicine, Osaka University Development of AAV vectors aiming the gene therapy for cardiomyopathy |
| 14:50-15:05 | Prof Shin Kwak Neurologist/Professor Department of Molecular Neuropathogenesis (Endowed Chair, GTRI) Tokyo Medical University Development of gene therapy for amyotrophic lateral sclerosis based on molecular mechanisms |
| 15:05-15:20 | Prof Hitoshi OKAZAWA Chair, Neurology, Medical Research Institute/Director, Center for Brain Integration Research, Tokyo Medical and Dental University Development of gene therapies of neurodegenerative diseases targeting new pathological mechanisms |
| Coffee Break (10min) | |
| Cell Therapy Session | |
| Opening Remark | |
| 15:30-15:35 | Opening Remark Prof Hiroshi SHIKU Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine |
| Session II: Cell Therapy - a focus on quality, efficacy and safety Chair: Prof Hiroshi SHIKU (Japan) |
|
| 15:35-16:05 | <Keynote Lecture> A/Prof John CONNOLLY Director for Translational Immunology, Institute of Molecular and Cell Biology (IMCB), A*STAR Systems based approach to monitoring cells therapy clinical trials |
| 16:05-16:35 | <Keynote Lecture> Prof Toshio SUDA Senior Principal Investigator, Cancer Science Institute of Singapore/ Professor, Department of Medicine, Yong Loo Lin School of Medicine, NUS Hematopoietic stem cells and their niche |
| Session III: Cell Therapy - Kick-off Presentations of SICORP Singapore Chair: A/Prof John CONNOLLY (Singapore), Prof Hiroshi SHIKU (Japan) |
|
| 16:35-16:55 | Dr Shoji SAITO (Japan) Assistant Professor, Shinshu University, Department of Paediatric, School of Medicine Dr Timothy Wai Ho Shuen (Singapore) Research Fellow, National Cancer Center Singapore Developing a safe and potentially efficacious piggyBac-based CAR-T cell strategy for virus-related cancers |
| 16:55-17:15 | Dr Tatsuto KAGEYAMA (Japan) Researcher, Kanagawa Institute of Industrial Science and Technology (KISTEC) Dr Michinao HASHIMOTO (Singapore) Assistant Professor, Singapore University of Technology and Design Large-scale Preparation of Hair Follicle Germs using Hydrogel Bioprinting |
| 17:15-17:35 | Dr Jun SHIRAKAWA (Japan) Assistant Professor, Yokohama City University, Graduate School of Medicine Dr Adrian Kee Keong TEO (Singapore) Principal Investigator, Institute of Molecular and Cell Biology, A*STAR Human stem cell-derived pancreatic beta cells for the treatment of diabetes |
| Panel Discussion | |
| 17:35-18:05 | Panellists: Dr Shoji SAITO (Japan) Dr Timothy Wai Ho Shuen (Singapore) Dr Tatsuto KAGEYAMA (Japan) Dr Michinao HASHIMOTO (Singapore) Dr Jun SHIRAKAWA (Japan) Dr Adrian Kee Keong TEO (Singapore) |
| Closing Remark | |
| 18:05-18:10 | A/Prof John CONNOLLY (Director for Translational Immunology, IMCB, A*STAR) |
| Reception | |
| 18:30-19:30 | Foyer at 10th floor of Nihonbashi Life Science Building (Supported by LINK-J) |
参加費
無料
定員
100名
主催
主催：国立研究開発法人日本医療研究開発機構（AMED）国際事業部・戦略推進部 難病研究課
共催：一般社団法人ライフサイエンス・イノベーション・ネットワーク・ジャパン（LINK-J）
お問い合わせ先
AMED運営事務局
E-mail : gene-cell-sympo@amed.go.jp
E-mail : gene-cell-sympo@amed.go.jp
