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【開催延期】LINK-J & UCサンディエゴ ジョイントウェビナーシリーズ 第1回 with 京都大学 最先端のナノエンジニアリングとドラッグデリバリー技術

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~最先端のナノエンジニアリングとドラッグデリバリー技術~

UCサンディエゴとLINK-Jでは、これまで、UCサンディエゴのトップ研究者を日本にお招きして、セミナーを共催して参りました。
今年度は、それに代えて、日本の大学とUCサンディエゴからそれぞれのトップ研究者をお招きするジョイントウェビナーをシリーズで開催することといたしました。
今回は、その第1弾として、UCサンディエゴからニコール・スタインメッツ教授を、京都大学から田畑泰彦教授をお招きし、ナノエンジニアリングとドラッグデリバリー技術の最新動向につき、ご講演いただきます。
使用言語:英語(同時通訳あり)

*English program available here


日時

2020年12月1日(火)8:30 – 10:00(日本時間)

会場

オンライン(ZOOMウェビナー使用)


参加申込

(外部サイトが開きます)

プログラム

8:30-8:35 Opening Remarks – A. Soyama, LINK-J
8:35-8:40 Remarks and Speaker Introduction – M. Waga, UC San Diego
8:40-9:00 Prof. Nicole F. Steinmetz, UC San Diego
9:00-9:05 Q&A on Prof. Steinmetz’s presentation - moderated by LINK-J & UCSD
9:05-9:25 Prof. Yasuhiko Tabata, Kyoto University
9:25-9:30 Q&A on Prof. Tabata’s presentation and transition – moderated by LINK-J & UCSD
9:30-9:50 Q&A and Discussion on future work and challenges to translation - moderated by LINK-J & UCSD
9:50-9:55 Closing Remarks & Announcement about Upcoming Webinars – A. Soyama

講演内容
講演1 Nicole F. Steinmetz Ph.D.
"NanoEngineering Gone Viral: Plant Virus-Based Immunotherapy and Vaccines"「急速に広まるナノエンジニアリング:植物ウイルスを用いた免疫療法とワクチンについて」

哺乳類には感染しない植物ウイルスのカプシドをプラットフォームとし、ナノエンジニアリングで加工したウイルス様粒子のライブラリを用いた医療応用、農業応用の研究開発を行っている。このような粒子は植物内で安価で高品質に生産することができ、輸送におけるコールド・チェーンも必要としないため、途上国での生産が期待できる。医療応用としては、植物ウイルス様粒子をがん細胞に接種し(in situ vaccination)、がん細胞の局所及びシステミックな免疫反応を誘導し、がんの転移及び再発を防止する新たながん免疫療法の研究を行っており、マウスや犬における試験結果の評価を紹介する。

講演2 Yasuhiko Tabata Ph.D.
"Drug Delivery Technologies for Future Advanced Medical Treatment"「将来の先進治療に向けたドラッグデリバリー技術について」

将来の先進的治療法の一つとして、生体が本来有する自然治癒力を利用した組織の再生医療が期待されている。生分解性のハイドロゲルを用いた組織再生部位周辺における細胞の増殖因子やケモカイン、遺伝子等の徐放化DDSにより、細胞の増殖と分化を促し、様々な組織の再生医療を実現することを目指している。

講演者略歴

3c445fce9e51844db080ec55fb12511d5856f678.pngNicole F. Steinmetz Ph.D. | Professor, Department of NanoEngineering and Center for Nano-ImmunoEngineering (nanoIE), Jacobs School of Engineering, UC San Diego

Dr. Steinmetz is a Professor of NanoEngineering at the University of California, San Diego (07/2018-present). She is the founding Director of the Center for Nano-ImmunoEngineering (nanoIE) and serves on the Leadership Team for a UC San Diego Materials Research Science and Engineering Center (MRSEC). She started her independent career at Case Western Reserve University School of Medicine in the Department of Biomedical Engineering (in 2010), where she was promoted through the ranks of Assistant, Associate, and Full Professor. Dr. Steinmetz trained at The Scripps Research Institute, La Jolla, CA where she was a NIH K99/R00 awardee and AHA post-doctoral fellow (2007-2010); she obtained her PhD in Bionanotechnology from the University of East Anglia where she prepared her dissertation as a Marie Curie Early Stage Training Fellow at the John Innes Centre, Norwich, UK (2004-2007). Her early training was at the RWTH-Aachen University in Germany. Dr. Steinmetz’s research program focuses on the engineering of plant virus-based nanomaterials targeting human and plant health applications, such as therapeutic delivery, molecular imaging, and next-generation vaccines and immunotherapies. Dr. Steinmetz has authored more than 190 journal articles (H index 50). Dr. Steinmetz is a standing member of the NIH Nanotechnology study section. She serves on the Editorial Board of Wiley Interdisciplinary Reviews (WIREs) on Nanomedicine and Nanobiotechnology; she serves on the Advisory Editorial Board for the ACS Nano, Molecular Pharmaceutics, Journal of Materials Chemistry B, and Materials Advances. Dr. Steinmetz is a Fellow of the Royal Society of Chemistry (FRSC, since 2018), a Fellow the American Institute of Medical and Biological Engineering (AIMBE, since 2017); she has won many awards, including an American Cancer Society (ACS) Research Scholar Award (2016), and a Young Innovator of Cellular and Molecular Bioengineering Award from the Biomedical Engineering Society (2015). Dr. Steinmetz’s research program is supported through grants from NIH, NSF, NIFA, CDMRP as well as ACS, Susan G. Komen, AHA, amongst other agencies. Over the past 10 years, Dr. Steinmetz has been awarded grants as PI and Co-PI totaling $41+ million in total costs.

dd75f19bb329c4b9188f24e9b5518b9d000197e4.jpgYasuhiko Tabata Ph.D. | Professor, Laboratory of Biomaterials, Department of Regeneration Science and Engineering, Institute for Frontier Life and Medical Sciences, Kyoto University

Dr. Yasuhiko Tabata is the Professor and Chairman of the Laboratory of Biomaterials at the Institute for Frontier Life and Medical Sciences, Kyoto University and a Professor of the Graduate School of Medicine, Osaka University, and guest professors at the Graduate School of Medicine, Dentistry, Pharmaceutical Sciences, and Engineering of 17 different universities. He received his BD in Polymer Chemistry (1981), Ph.D. (1988) in Technology, D.Med.Sc. (2002), and D.Pharm. (2003) all at Kyoto University. He was a Visiting Scientist at the MIT (Professor Robert Langer) (1991-92). He has published 1,710 scientific papers including 146 book chapters and review articles, and has 130 patents. He received the Young Investigator Award (1990), the Scientific Award from the Japanese Society for Biomaterials (2002), the Scientific Award from the Japan Society of Drug Delivery System (2011), Chandra P. Sharma Award of the International Society of Biomaterials & Artificial Organs (2011), the Scientific Award from the Japanese Society for Regenerative Medicine (2014), Merit Award Winners for Industry-Academia-Government Collaboration, President of Science Council of Japan Award (2016), Outstanding Scientist Award of the Tissue Engineering and Regenerative Medicine International Society - Asian-Pacific Chapter (TERMIS-AP) (2018), and several awards.
Dr. Tabata is the board member of the Japanese Society of Regenerative Medicine (JSRM), the Japanese Society for Biomaterials (JSB), the Japan Society of Drug Delivery System (JSDDS), and the Japanese Society of Inflammation and Regeneration (JSIR) or the councilor of the Japanese Society of Wound Healing, the Japanese Artificial Organ Society, He is an associate member of the Science Council of Japan, Cabinet Office, a fellow of the World Biomaterials Society (WBS), the TERMIS, the Controlled Release Society (CRS) or the New York Academy of Science and American Institute for Medical and Biological Engineering (AIMBE), and the Founding Fellow for Tissue Engineering and Regenerative Medicine, (FTERM).
Dr Tabata is the one of founder members of Asian Biomaterial Federation (ABF). He is a board member of Tissue Engineering Society International for 2001-2003 and 2012-present. He organized as the chairman the 13th Annual Congress of JSRM (2014) and the 37th Annual Congress of JSB (2015), the 37th Annual Congress of JSIR (2016), and the 33th Annual Congress of JSDD (2017). He is a board member of TERMIS-AP for 2013-present and the president of TERMIS-AP for 2016-2020, and chairs the 5th TERMIS World Congress 2018, Kyoto, Japan.
His research is very interdisciplinary in nature and brings together the fields of polymer chemistry, pharmaceutical science, biology, and basic and clinical medicines. He actively proceeds translational researches by linking bioengineering scientists, clinicians, and industry to achieve clinical therapies of regenerative medicine as well as produce some commercialization products for basic researches and cosmetics. His research focuses on the design and preparation of biodegradable or non-biodegradable biomaterials for their biological, medical, and pharmaceutical applications, while the keywords are biomaterials, drug delivery system (DDS), tissue engineering, regenerative medicine, stem cell technology, and medical diagnostics.

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