培養組織に対する物理刺激による機能化 "Mechano-Driven Functionalization of Engineered Tissues" Session 3 Biomaterials/Nanomaterials

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LINK-J & UCサンディエゴ ジョイントウェビナーシリーズ 第7回 with 大阪大学国際医工情報センター


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日本時間 内容
9:00-9:05 Welcome - Akihiko Soyama, LINK-J and Miwako Waga, UC San Diego
Remarks - Dr. Masahiro Kino-oka, MEI Center, Osaka University & Dr. Andrew McCulloch, UC San Diego
9:05-9:35 Presentation - "Injectable Biomaterials for Translational Regenerative Engineering & Drug Delivery"
Dr. Karen L. Christman, Professor of Bioengineering & Associate Dean for Faculty, Jacobs School of Engineering, UC San Diego
9:35-10:00 Presentation - Tissue engineering based on enzymatic crosslinking and degradation
Dr. Shinji Sakai, Professor, Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
10:00-10:14 Q&A and Discussion - moderated by Drs. Kino-oka and McCulloch
10:14-10:15 Closing Remarks - A. Soyama


This talk will cover injectable biomaterial based strategies to encourage endogenous tissue healing as well as for drug delivery for several applications in cardiovascular disease and women's health.

Enzymes which function under mild condition for mammalian are attractive tools in tissue engineering. The substrate specificity and mild reaction condition enable us to manufacture and modify the environment around cells without causing adverse effects. My lab’s main works are developments of hydrogels gellable through enzymatic cross-linking and degradable using enzymes, and applications of the hydrogels to tissue engineering. Especially, we focus on the use of horseradish peroxidase for hydrogelation and the use of natural polymers. In addition, we are developing 3D bioprinting techniques suitable for the enzymatic hydrogelation. Apart from these works, we are developing genome-editing technologies using biocompatible polymers. I will introduce these recent works in my presentation.


ADM-683x1024.jpegDr. Andrew McCulloch, Distinguished Professor of Bioengineering and Medicine; Director, Institute of Engineering in Medicine, UC San Diego

Dr. Andrew McCulloch is Distinguished Professor of Bioengineering and Medicine at the University of California San Diego and Director of the Institute for Engineering in Medicine. He earned his bachelor (1981) and Ph.D. (1986) degrees in Engineering Science at the University of Auckland and joined the UC San Diego faculty in 1987. He directs the UCSD Interfaces Graduate Training Program and the Interdisciplinary Ph.D. Specialization in Multi-Scale Biology. Dr. McCulloch served as Vice Chair of the Bioengineering Department from 2002 to 2005 and Chair from 2005 to 2008. He is also a member of Qualcomm Institute, the Center for Research on Biological Systems, and a Senior Fellow of the San Diego Supercomputer Center.

kino-oka2.png紀ノ岡 正博 先生 大阪大学大学院工学研究科 生物工学専攻 生物プロセスシステム工学領域 教授

1989年03月大阪大学 基礎工学部 化学工学科 卒業 学士
1991年03月大阪大学 基礎工学研究科 化学系専攻 修了 修士
1991年06月 ~ 2000年01月大阪大学助手
1996年01月大阪大学 基礎工学研究科 工学博士
2000年02月01日 ~ 2003年03月31日,基礎工学研究科 物質創成専攻,講師,専任
2003年04月01日 ~ 2007年03月31日,基礎工学研究科 物質創成専攻,助教授,専任
2007年04月01日 ~ 2009年03月31日,基礎工学研究科 物質創成専攻,准教授,専任
2009年04月01日 ~ 2020年03月31日,工学研究科 生命先端工学専攻,教授,専任
2020年04月01日 ~ 継続中,工学研究科 生物工学専攻,教授,専任

Christman%202018%20headshot.jpgDr. Karen L. Christman, Professor of Bioengineering & Associate Dean for Faculty, Jacobs School of Engineering, UC San Diego

Christman's research group focuses on developing novel biomaterials for tissue engineering and regenerative medicine applications. The lab has a strong translational focus with the main goal of developing minimally invasive, biomaterials based therapies for myocardial infarction, heart failure, peripheral artery disease and "women's health." Projects are highly interdisciplinary and involve collaborations with basic scientists, engineers and physicians.
She joined the Department of Bioengineering at UC San Diego in 2007 and is a member of the Institute of Engineering in Medicine and the Sanford Consortium for Regenerative Medicine. She is a fellow of the American Heart Association and the American Institute for Medical and Biological Engineering. She is also co-founder of Ventrix, Inc., which is in clinical trials with the cardiac extracellular matrix hydrogel technology developed in her lab at UC San Diego.
She received her B.S. in Biomedical Engineering from Northwestern University in 2000 and her Ph.D. from the University of California San Francisco and Berkeley Joint Bioengineering Graduate Group in 2003, where she examined in situ approaches to myocardial tissue engineering. She was also a NIH postdoctoral fellow at the University of California, Los Angeles in the fields of polymer chemistry and nanotechnology.

prof%20sakai.png境 慎司 先生 大阪大学大学院基礎工学研究科 教授

1994年 福岡県立明善高等学校 卒業
1998年 九州大学工学部化学機械工学科 卒業
2000年 九州大学大学院物質プロセス工学専攻修士課程 修了
2002年 九州大学大学院物質プロセス工学専攻博士課程 修了・博士(工学)
2002年10月~2009年12月 九州大学大学院工学研究院 助手・助教
2010年1月~2016年3月 大阪大学大学院基礎工学研究科・准教授
2016年4月~現在 大阪大学大学院基礎工学研究科・教授




主催:LINK-J、共催:UC San Diego